New research in today’s age increasingly focuses on the subjects which can help in fighting the current and any future health challenges. Therefore, a person may see scientists now looking at previously ignored spheres that may aid in treatments and therapies as well as the potential risk factors that were not taken into consideration before.
In doing so, there have been various discoveries which pave the way for further research and even disapprove of the beliefs health in the past. Secondly, the adoption of new methodologies has paved the way for researchers to study connections within bodily procedures.
This has led to an increase in knowledge of how one health issue may lead to another or how multiple factors work in combination to cause the development of a health condition. For instance, the gut bacteria has been recently researched upon much more than ever before.
The reason for this is that studies have linked the gut bacteria to a number of different benefits and highlighted their importance in maintaining the health of the person.
Studies from the past even link problems in gut bacteria to health issues like autism, anxiety, problems in brain function and many more along with gastrointestinal health issues.
Recently, another new study accentuates the significance of the gut bacteria when it comes to management and prevention of food allergies.
Conducted by researchers from Boston Children’s Hospital and Brigham and Women’s Hospital, the study does more detailed research on the subject at a cellular level. The findings of the study can be found in the journal Nature Medicine.
How Was the Study Conducted?
The treatment for food allergies at the moment is mainly either prevention and oral immunotherapy. In the majority of the people, the results vary and are not as good in every person taking the therapy. The new research sheds light on how this problem can be resolved.
Medical literature present on the gut microflora of people with food allergies shows that these people do not have particular species of the bacteria in their gut. The researchers provide a solution to this by the introduction of human-origin and cultural bacteria.
This can not only make the immune system of the person tolerant to one specific food allergy but may actually treat all of them.
In order to test and see the results of this theory, the scientists first took stool samples of children and infants both with and without food allergies. Like the previous studies showed, there were differences in the gut microbiota between children with food allergies and the ones without them.
After this confirmation, the team moved on to introducing specific strains of gut bacteria in lab mice who had a sensitivity to eggs.
The scientists were able to figure out the main differences in the gut bacteria of children with allergies and without them using advanced technology. Consequently, two groups of bacteria, Clostridiales or Bacteroidetes, were seen to be different and were introduced in mice.
What Were the Results?
After the introduction of the bacteria, the researchers noted that both of the species protected the mice from the egg allergy and using other species of bacteria did not have the same effect.
In addition, the researchers also observed closely at how this happens at a cellular level and found that the two bacteria stimulated regulatory T cells and affected a total of two immune pathways.
While the experiment was successful, the researchers agree that the results can only be, for the time being, limited to mice and can be hard to replicate in humans. However, they are still hopeful and aim at carrying out a similar experiment in children in the near future.