An International Collaboration Led to Discovering New Causes of Prostate Cancer

An International Collaboration Led to Discovering New Causes of Prostate Cancer


African men are the most prone to get Prostate Cancer in the world. International research is being conducted by the experts from England of the University of Birmingham, and of the University of Nottingham. The experts from the Kenya Medical Research Institute (KEMRI) are so collaborating with them to find out more about Prostate Cancer.

They are working on the patients from England as well as from Kenya to find out the functioning of immune cells and signals on the functioning of the prostate gland.

They have already found out the functioning and effect of a protein called PRH. PRH (proline-rich homeodomain protein) that controls the overgrowth of prostate cells or prevents them from invading other cells. Not only this, but it also makes sure the regulation of other genes, by doing so it regulates the response of prostate grand to the immune signals. This cancer grows as the level of PRH decrease.

After they have found the direction to work on how the collaboration of these international experts is working on how the alteration in the levels of the protein, PRH, will alter the response of the cells to immune signals.

This new research is funded by Kenya National Research Funds and UK Medical Research Counsel. The Medical Research Counsel is known to provide funds to researchers in the entire medical spectrum, in the UK as well as in Africa. Right now this research team is provided by huge funds of $837,252.

This research is led by Dr. Sheela Jayaraman from the University of Birmingham, Dr. Veronica Manduku the Deputy Director of KEMRI and Professor Kevin Gaston from the University of Nottingham.

It shouldn’t be forgotten that this research could of great advantage as Prostate Cancer is the most common cancer among the men.

The reason to conduct this research on the patients in Kenya is that the men with African origin are at a higher risk of getting this disease. The cases of Prostate Cancer that were recorded in a recent year were 47,000 in number and this number doesn’t seem to be decreasing as men have a longer life span.

The number of cases reported in the undeveloped and developing countries is also increasing. The expenses in the treatment and loss of lives due to this disease are hindering economic growth in the country.

Dr. Sheela has pointed out some of the treatments in the advanced stage of Cancer that are Gene therapy and drug treatment. She also told that this treatment is not needed at the less advanced stage of disease as cancer won’t spread.

If they could find better ways to identify patients who needed the treatment would be of great importance in research. Dr. Veronica also stated that the role of PRH protein in treating Prostate Cancer will lead to more cost efficient. Professor Kevin thinks of the opportunity of working on this research, a proud moment. He says that Prostate Cancer is a global issue, this research will help them record the immune signals in blood and PRH effecting it.



Maddox Perry

Maddox is communication and political sciences graduate and working as a news journalist for the last 4 years. He is a freelance writer at Reportshealthcare. The focus areas of Maddox are global politics, climate change, public policy, and law. He feels that the environment directly impacts every individual's health and every government should ensure this clean environment and health facilities as basic rights of every citizen.

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