Coriandrum sativum (L.) Seed Extract to prevent Heart Failure in Rats

 Coriandrum sativum (L.) Seed Extract to prevent Heart Failure in Rats

The Journal of Dietary Supplements has published a study stating that herbs like coriander offer protective effects against heart failure. The researchers at Hamdard Institute of Medical Sciences and Research (HIMSR) and Jamia Millia Islamia University in India carried out the respective study. They evaluated the therapeutic and protective effects of coriander extract on heart failure.

Taking good care of your heart is crucial for healthy survival. The heart is a delicate organ but works strenuously all the time. In order to let it work efficiently, we must protect it anyway. Eating a diet rich in vegetables and fruits and exercising daily are the basic heart-friendly activities one must adapt.

This respective research states that coriander is one of the best food choices to keep the heart healthy, protecting it against failure.

The researchers carried out the study on rats. They administered isoproterenol in rats to stimulate heart failure. Isoproterenol is a synthetic drug causing a faster heart rate and an elevated cardiac output. The drug was given for two weeks. The rats successfully developed cardiac failure and experienced severe impairment in left ventricular functions. Moreover, they exhibited reduced baroreflex sensitivity and notable changes in blood flow and lipid profile.

The left ventricle of the heart pumps oxygenated blood to the tissues around the body. Baroreflex sensitivity accounts for regulation of blood pressure. The rats with cardiac failure also had increased lipid peroxidation. It damaged their cell membranes, lipoproteins, and other molecules containing lipids. Moreover, lipid peroxidation increased the expression of endothelin receptors as well.

The researchers then fed the rats with coriander extract which improved their left ventricular functions, blood flow, and baroreflex sensitivity dramatically. In addition, the extract suppressed lipid peroxidation, enhanced lipid profile, and condensed the expression of endothelin receptors.

Thus, the results of the study indicated that coriander extract can significantly protect the heart against failure. The researchers attribute these protective effects of coriander to its ability to perk up left ventricular functions and baroreflex sensitivity, diminish lipid peroxidation, and regulate the expression of endothelin receptors.

The results of the study conclude that consuming coriander protects the heart from damage like heart failure.

Coriander (Coriandrum sativum) is also known as cilantro. It packs a variety of nutrients in its stems, leaves, seeds, essential oil, and roots. Along with greater healing capabilities, coriander serves as a rich source of,

  • Dietary fiber
  • Manganese
  • Iron
  • Magnesium
  • Vitamin C and K
  • Proteins

It also contains small amounts of calcium, phosphorus, potassium, thiamin, niacin, and carotene. Following are some of the health benefits of eating coriander,

Coriander contains potent antioxidants such as alkanols, apigenin, catechins, and linalool. These antioxidants fight the free radicals and thus reduce the risks of oxidative damage.

The antioxidant properties of the herb also help it to prevent cancer. Research shows that coriander root extracts inhibit DNA damage. Moreover, it prevents the migration of the cancerous cells and promotes cancer cell death.

A study, published in the Journal of Food Science, states that the leaf and stem extracts of coriander can significantly lower blood sugar levels. These extracts also help beta-cells to regenerate and improve blood sugar control.

Coriander extract also decreases the levels of cholesterol in your body. It targets the total cholesterol, low-density lipoprotein (LDL) cholesterol, and triglycerides.

Coriander oil possesses notable antifungal and antimicrobial effects. Thus, it can be used in treatment against yeast infections. It has the ability to break down the cell wall of the pathogens and prevent them from multiplying.

Studies also link coriander to eliminate toxic metals like lead from the body. This makes the herb an excellent tool for protection from lead poisoning.

Coriander extracts boost memory as well. The respective herb reverses memory deficits. According to a mice study, it also manages conditions like Alzheimer’s disease.



The author is a Medical Microbiologist and healthcare writer. She is a post-graduate of Medical Microbiology and Immunology. She covers all content on health and wellness including weight loss, nutrition, and general health. Twitter @Areeba94789300

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